Prof. Dr. med. Simone Wagner

Qualifikationen

2000                         EMG Zertifikat der DGKN

2001                         Ultraschall Zertifikat der DGKN

2001                         Fachärztin für Neurologie

2008                         Zusatzbezeichnung Spezielle Schmerztherapie

2010                         Qualifikation Verkehrsmedizin

2014                         Qualifikation fachgebundene genetische Beratung

Mitgliedschaften:

​Deutsche Gesellschaft für Neurologie

Deutsche Gesellschaft für Neurologische Intensivmedizin

Deutsche Gesellschaft für klinische Neurophysiologie

Berufsverband Deutscher Neurologen

Deutsche Gesellschaft für Neurowissenschaftliche Begutachtung

Vereinigung der Neurologen in Baden-Württemberg

Ärztenetz Schwetzingen

Deutscher Ärztinnenbund

Publikationen:

Wagner, S., Tagaya M., Koziol, J. Quaranta V., del Zoppo G.J. 1997 Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin a6b4 during focal cerebral ischemia/reperfusion Stroke 28: 858-865

Wagner S., Gardner H. 2000 Modes of regulation of laminin-5 production by rat astrocytes.  Neurosci Let 284:105-108

Wagner S., von Waldenfels A., Meinck H.M. 2000 Gating of segmental and transcortical reflexes to human hand muscles depends on the mode of innervation Neuroci Let 280: 127-130

Tagaya M, Haring H.P., Stuiver I., Wagner S., et al. 2001 Rapid loss microvascular integrin expression during focal brain ischemia reflects neuron injury. JCBFM 21: 835-846

Wagner S., Kalb, P. et al. 2002 Activation of the tissue kallikrein-kinin system in stroke J Neurol Sci 202: 75-76

Garcia J.H., Wagner S. et al.  1995 Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats 26: 627-635

Wagner, S. Nagel S. et al, 2003 Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermia Brain Res 984_63-75

Horstmann, S, Kalb, P., Koziol, J., Garner H., Wagner S. 2003 Profiles of matrix metalloproteinases, their inhibitors and laminin in stroke patients 34: 2165-2170

Nagel, S., Sandy, J.D., Meyding-Lamade, U., Schwark, C., Bartsch, J.W., Wagner, S., 2005. Focal cerebral ischemia induces changes in both MMP-13 and aggrecan around individual neurons. Brain Res. 1056, 43-50. (IF 2,62)

Horstmann, S., Su, Y., Koziol, J., Meyding-Lamade, U., Nagel, S., Wagner, S., 2006. MMP-2 and MMP-9 levels in peripheral blood after subarachnoid hemorrhage. J Neurol Sci. 251, 82-6. (IF 2,16)

Nagel, S., Genius, J., Heiland, S., Horstmann, S., Gardner, H., Wagner, S., 2007. Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain Res. 1132, 210-7. (IF 2,62)

Grond-Ginsbach, C., Hummel, M., Wiest, T., Horstmann, S., Pfleger, K., Hergenhahn, M., Hollstein, M., Mansmann, U., Grau, A.J., Wagner, S., 2008. Gene expression in human peripheral blood mononuclear cells upon acute ischemic stroke. J Neurol. 255, 723-31. (IF 3,85)

Nagel, S., Su, Y., Horstmann, S., Heiland, S., Gardner, H., Koziol, J., Martinez-Torres, F.J., Wagner, S., 2008. Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase. Brain Res. 1188, 198-206. (IF 2,62)

Horstmann, S., Koziol, J.A., Martinez-Torres, F., Nagel, S., Gardner, H., Wagner, S., 2009. Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression. J Neurol Sci. 276, 75-8. (IF 2,16)

Horstmann, S., Budig, L., Gardner, H., Koziol, J., Deuschle, M., Schilling, C., Wagner, S., 2010 Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease. Int Psychogeriatr. 22, 966-72. (IF 2,47)

Nagel, S., Heinemann, P.V., Heiland, S., Koziol, J., Gardner, H., Wagner, S.2011, Selective MMP-inhibition with Ro 28-2653 in acute experimental stroke--a magnetic resonance imaging efficacy study. Brain Res. 1368, 264-70. (IF 2,62)

Nagel, S., Papadakis, M., Pfleger K., Grond-Ginsbach C., Buchan A.M. Wagner, S. 2012 Neuroscience 208, 109-122  Pathway and network analysis of the global gene expression profile under normo- and hypothermic conditions after transient focal cerebral ischemia Neuroscience (IF3,2)

Grünig, E., Maier, F., Ehlken, N., Fischer C., Lichtblau, M., Blank, N., Fiehn, C., Stöckl, F., Prange, F., Staehler, G., Reichenberger, F., Henning, T., Halank, M., Seyfarth, H.J., Wagner, S*., Nagel, C.*, 2012 accepted Exercise training in pulmonary arterial hypertension associated with connective tissue diseases Arthritis Research &Therapy (IF 4,3) *equally contributed

Martinez-Torres, F.J., Wagner, S., Haas, J., Kehm, R., Sellner, J., Hacke, W., Meyding-Lamade, U., 2004. Increased presence of matrix metalloproteinases 2 and 9 in short- and long-term experimental herpes simplex virus encephalitis. Neurosci Lett. 368, 274-8. (IF 2,05)

Koziol, J.A., Wagner, S., Sobel, D.F., Feng, A.C., Adams, H.P., 2005. Asymmetries in the spatial distributions of enhancing lesions and black holes in relapsing-remitting MS. J Clin Neurosci. 12, 895-901. (IF 1,16)

Veltkamp, R., Bieber, K., Wagner, S., Beynon, C., Siebing, D.A., Veltkamp, C., Schwaninger, M., Marti, H.H., 2006. Hyperbaric oxygen reduces basal lamina degradation after transient focal cerebral ischemia in rats. Brain Res. 1076, 231-7. (IF 2,62)

Arnold, M.L., Lichy, C., Werner, I., Radbruch, A., Wagner, S., Grond-Ginsbach, C., 2008. Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population. Thromb Haemost. 100, 614-7. (IF 4,7)

Grond-Ginsbach, C., Horstmann, S., Hummel, M., Wiest, T., Honold, C., Pfleger, K., Hergenhahn, M., Hollstein, M., Weninger, A., Knyazev, Y., Mansmann, U., Wagner, S., Grau, A.J., 2009. Increased expression of cell-cell signaling genes by stimulated mononuclear leukocytes in patients with previous atherothrombotic stroke. A whole genome expression profile study. Eur Neurol. 62, 30-9. (IF 1,76)

Reviews

Dirks, M., Niessen, L.W., Koudstaal, P.J., Franke, C.L., van Oostenbrugge, R.J., Dippel, D.W. et al. , 2007. Intravenous thrombolysis in acute ischaemic stroke: from trial exclusion criteria to clinical contraindications. An international Delphi study. J Neurol Neurosurg Psychiatry. 78, 685-9.

Saver, J.L., Hacke, W., Wagner, S., 2005a. What is the safety, effectiveness, and feasibility of supplemental oxygen in acute stroke? Circulation Research. 112, B1-B14.

Buchbeiträge

Diener, H.C., Wagner, S., Hacke, W., Weiller, C., 2006. Schlaganfall und  assoziierte Krankheiten im Alter. In: Gerontoneurologie. Vol., G. Deuschl, H. Reichmann, ed. Georg Thieme Verlag, Stuttgart, pp. 123-133.

Hamann, G.F., Wagner, S., 2006. The vessel wall in thrombosis: relevance to acute stroke therapy. In: Thrombolytic and Antithrombotic Therapy for Stroke. Vol., J. Bogousslavsky, W. Hacke, ed. Informa uK Ltd, Abingdon UK, pp. 31-45.

Patel S.C., Wagner S., Garcia J.H. 2008 The vasculature of the human brain. In: Neurosciene in Medicine. Conn P.M. ed. J.B. Lippincott Company

Wagner, S., Lichy, C., Hacke, W., 2011. Zerebrale Ischämie, ischämischer Schlaganfall. In: Hämostaseologie für die Praxis. Vol., H.D. Bruhn, C.M. Schambeck, V. Hach-Wunderle, ed. Schattauer GmbH, Stuttgart, pp. 357-368. 2. Vollständig überarbeitete, erweiterte Auflage.